Non-PhD position. The incumbent is responsible for supporting antigen discovery, antigen optimization, and the development of assays of protein quality. In addition, the incumbent will assist with the preclinical evaluation and early clinical development of candidate viral vaccines. The incumbent will assist with protein production in cell culture, with chromatographic protein purification, and with a variety of protein analytic tests. In addition, as needed, the incumbent will perform various assays to monitor the immune responses elicited by vaccine candidates. This position will also be responsible for maintaining cell lines, growing and purifying viruses, and daily laboratory operations. Work is to be done in a compliant manner according to relevant SOP guidelines and cGLP and/or cGMP guidelines where appropriate. The incumbent will be part of a dynamic team and should possess a strong work ethic and collaborative spirit.
Support recombinant protein expression, purification, and molecular biology through cell culture expression, chromatographic protein purification, and a variety of protein analytical techniques. Analyze immune responses to vaccine candidates using techniques that include (but are not limited to) cell culture, neutralization assays, ELISAs, and Octet for antibody characterization. Grow viruses and maintain viral stocks as needed. Independently interpret and summarize experimental data. Present experimental results at group meetings. Generate and characterize reagents used to perform necessary assays and support maintenance of laboratory supplies. Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy. Performs other duties as assigned. Satisfactorily complete all safety training in conformance with Departmental requirements. Where applicable, performs job responsibilities in compliance with cGMP/GLP and all other regulatory agency requirements.
Basic laboratory training in aseptic technique is essential. Ability to work with infectious agents safely. The capacity to work effectively in a highly visible research program with time-constrained milestones.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
#LI-PHEN (Other) (United States of America)
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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