ROLE SUMMARY The incumbent is responsible for supporting the preclinical evaluation and early clinical development of candidate viral vaccines. The incumbent will develop and perform various assays to monitor the cellular and antibody immune responses elicited by vaccine candidates. This position will also be responsible for maintaining sample inventory for different studies and preparing samples for testing. Work is to be done in a compliant manner according to relevant SOP guidelines and current Good Laboratory Practice (cGLP) and/or Good Manufacturing Practice (cGMP) guidelines where appropriate. The incumbent will be part of a dynamic team and should possess a strong work ethic and collaborative spirit.
Develop and perform ELISpot/FluoroSpot-based assays to measure cellular (B-cell and T-cell) immune response to vaccine candidates in preclinical and clinical studies.
Perform flow cytometry to investigate the cellular phenotype and function.
Analyze antibody responses to vaccine candidates using techniques that include (but are not limited to) cell culture, hemagglutination inhibition assays, neutralization assays, ELISAs.
Analyze, document and report data in accordance with Pfizer/cGLP requirements. In collaboration with manager, interpret and summarize experimental data. Present experimental results at group meetings.
Generate and characterize samples and reagents used to perform necessary assays and support maintenance of laboratory supplies.
Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy.
Performs other duties as assigned to support the group with different projects.
Satisfactorily complete all safety training in conformance with Departmental requirements. Where applicable, performs job responsibilities in compliance with cGMP/GLP and all other regulatory agency requirements.
B.S. with 6 years of laboratory research experience.OR Master's degree in Immunology or Virology with 2 years of research experience
Industry experience is a plus.
Knowledge of methods in cellular immunology is highly preferred.
Proficiency with personal computers including Word, Excel or GraphPad Prism, PowerPoint and relevant scientific software is desirable.
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EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. N (Other) (United States of America) Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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* The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.